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EVE Comparative Visualizer Version 4.0 Released

San Diego, CA (April 10, 2006) – Eidogen-Sertanty has announced a new release of the EVE™ Comparative Visualizer software.  EVE version 4.0 contains several significant feature enhancements including:

  • Import proprietary protein structures directly into an EVE Project file
    • Automatically annotates ligand-binding sites on imported co-crystal structures
    • Automatically computes structure and site alignments to all other proteins in the EVE Project
    • Coupled with EVE's SDF Import functionality, EVE now enables full proprietary structure and proprietary ligand binding mode analysis workflows, while also allowing you to compare proprietary structures, sites, and ligands, with public and modelled data exported from the TIP knowledgebase.
  • Customize EVE Menus and Toolbar buttons
    • Combine EVE commands to create your own buttons that easily execute common tasks.
    • WebHelp for commands is available from the TIP Support site
  • Save the state of EVE Project Files
    • Preserves imported structures and sites, imported ligands, current masters, SLiC weightings, sorting modes, and customized menus
    • Facilitates easier transfer of EVE Project data between scientists, allowing only the relevant data to be shown for a particular project

About EVE
The Eidogen Visualization Environment (EVE) is an integrated environment for the comparative analysis of biological and chemical structures, providing the client-side interface for visualization of structural data exported from Eidogen-Sertanty's Target Informatics Platform (TIP™) and allowing users to interrogate it with their own small molecule data.   Key Features of EVE include:

  • Easy-to-use interface, coupled with project manipulation and customization capabilities fosters efficient communication and sharing of data among project team members
  • Rapidly perform side-by-side comparisons and overlays of whole protein structures or individual binding sites using pre-computed alignments
  • Integrated Chemogenomic Analysis Tools:
    • Site-Ligand Contact (SLiC™) analysis for comparison of ligand binding modes and high-throughput analysis of binding poses from docking analyses
    • LigandCross™ for creation of novel ligand scaffolds from bound ligands

About Eidogen-Sertanty, Inc.
Eidogen-Sertanty, formed in March 2005 from the merger of Eidogen and Sertanty, is a privately held company providing pioneering knowledge-driven discovery solutions to biotechnology and pharmaceutical organizations.  Eidogen-Sertanty’s unique and powerful suite of software, databases, and drug discovery services enable customers and collaborators to apply a knowledge-driven discovery approach to a variety of workflows and processes, including target selection and prioritization, library building and compound prioritization, and lead design and optimization.  To find out more about Eidogen-Sertanty and their products and services please visit www.eidogen-sertanty.com.

Contact Information:
Steven Muskal
760-729-0211
pr@eidogen-sertanty.com